Biological Use Authorizations

Biological Use Authorizations

January 21, 2014

Research Requiring IBC Approval

UCLA is responsible for ensuring that all research and teaching laboratories working with hazardous biological materials, regardless of funding source, is conducted a safe manner and is compliant with regulatory guidelines and policy. It is the responsibility of the Principal Investigator to seek Institutional Biosafety Committee (IBC) approval for the safe handling, transport, use and disposal of hazardous biological materials within their laboratory spaces and maintain an IBC approval during the time period these materials are used.  Modifications to protocols must also be approved by the IBC

Institutional Biosafety Committee (IBC)

The Institutional Biosafety Committee (IBC) is a faculty-led committee of experts in biosafety-related fields established to oversee research involving recombinant DNA and other biohazards.  The IBC is responsible for the oversight of all research activities involving recombinant and synthetic DNA and biohazardous material, as required and outlined in the NIH rDNA Guidelines and CDC Biosafety in Microbiological and Biomedical Laboratories (BMBL).  Research involving recombinant DNA and biological materials must be reviewed and approved by the IBC prior to the initiation of research.  For more information, IBC forms and submittlas please visit the ORA-IBC web page.

Here are common IBC Policies:

IBC policy on open flames in the BSC

IBC policy for human/NHP cells and tissues

IBC policy for reporting rDNA/Biohazardous incidents

EH&S Biosafety Pre-Review

Researchers submit protocols to the IBC, who reviews the protocols and proposed safety plans and determines if the risks have been reduced to an acceptable level.  The Office of the IBC, under Research Administration (ORA-IBC) administers the protocol submissions and coordination with IBC members.  The Biosafety office works in close collaboration with the IBC by doing a pre-review of protocols that ensures all relevant information is provided to the IBC to facilitate this process.  In addition, the Biosafety Office serves as the IBC’s “eyes and ears” conducting onsite inspections and risk assessments to ensure researchers’ submissions meet all IBC requirements.